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USF Department of Pediatrics
Children's Research Institute

Heartbeats of the Linask Lab - Dr. Kersti K. Linask

Publications

Publications

Listed below or search PubMed by entering "Linask KK" at the following link: PubMed

Linask, Kersti K. and Lash, J.W.  1986.  Precardiac cell migration:  Fibronectin localization at mesoderm-endoderm interface during directional movement.  Dev. Biol.  114:87-101.

Lash, J.W., Linask, Kersti K. and Yamada, K.M. 1987.  Synthetic peptides that mimic the adhesive recognition signal of fibronectin:  Differential effects on cell-cell and cell-substratum adhesion in embryonic chick cells.  Dev. Biol.  123:411-420.

Linask, Kersti K. and Lash, J.W. 1988. A role for fibronectin in the migration of avian precardiac cells I. Dose-dependent effects of anti-fibronectin on normal precardiac cell migration and heart development in early chick embryos.  Dev. Biol.  129:315-323.

Linask, Kersti K. and Lash, J.W. 1988. A role for fibronectin in the migration of precardiac cells.  II. Rotation of the heart forming region in embryonic chicks.  Dev. Biol.  129:324-329.

Greene, R.M., Linask, Kersti K., Pisano, M.M., and Lloyd, M.R. 1989.  Characterization of soluble cyclic AMP-dependent  protein kinase isozymes in murine embryonic palatal tissue.. J. Craniofac. Genetics and Dev. Biol.  9:207-222.

Linask, Kersti K. and R.M. Greene.  1989.  Ontogenetic analysis of embryonic palatal type I and type II cAMP-dependent protein kinase isozymes.  Cell Differentiation & Development 28:  189-202.

Linask, Kersti K. and R.M. Greene.  1989.  Subcellular compartmentalization of cAMP-dependent protein kinase regulatory subunits during palate ontogeny.  Life Sci. 45:1863-1868.

Linask, Kersti K. and J.W. Lash.  1990. Fibronectin and integrin distribution in migrating precardiac mesoderm cell.  Annals NY Acad. Sci. on "Embryonic Origins of Defective Heart Development." 588: 417-420.

Linask, Kersti K., M. D'Angelo, A.L. Gehris, and R.M. Greene.  1991.  Transforming growth factor-§ receptor profiles of human and murine embryonic palate mesenchymal cells.  Exp. Cell Res. 192:1-9.

Greene, R.M., Kersti K. Linask, M.M. Pisano, W. Weston and M.R. Lloyd.  1991. Transmembrane and intracellular signal transduction during palatal ontogeny.  J. Craniofacial  Genetics and Dev Biol. 11: 262-276.

Linask, Kersti K.  1992.  N-Cadherin localization in early heart development and polar expression of Na, K-ATPase and integrin during pericardial coelom formation and epithelialization of the differentiating myocardium.  Dev. Biol.  151:213-224.

Linask, Kersti K. and J.W. Lash. 1993.  Early heart development:  Dynamics of endocardial cell sorting suggests a common origin with cardiomyocytes.  Dev. Dynamics. 195:62-69.

Linask, Kersti K. and Yong-Hao Gui. 1995.  Inhibitory effects of ouabain on cardiomyogenesis and early heart development. Developmental Dynamics. 203, 93-105.

Canete-Soler, R. Yong-Hao Gui, Kersti K. Linask, and Ruth J. Muschel.  1995.  Developmental expression of MMP-9 (Gelatinase B) mRNA in mouse embryos.  Developmental Dynamics.  204, 30-40.

Canete-Soler, R. Yong-Hao Gui,  Kersti K.Linask, and Ruth J. Muschel.  1995.  Expression of MMP-9 (Gelatinase B) mRNA is associated with development of the embryonic mouse brain and coincides with vascularization.  Dev. Brain Res.  88,37-52.

Kostetskii, Igor, Kersti K. Linask, and Maija H. Zile. 1996. Vitamin A deficiency and the expression of retinoic acid receptors (RARs) in early quail embryo.  RouxÕs Archives of Dev. Biol. 12-23.

Tsuda, T., Nancy Philp, Maija H. Zile, and Kersti K. Linask.  1996.  Left-right asymmetric localization of flectin in the extracellular matrix during heart looping.  Dev. Biol. 173:  39-50.

Gui, Yong-Hao, Kersti K. Linask, Pongsak Khowsathit, and James C. Huhta.  1996.  Doppler echocardiography of normal and abnormal embryonic mouse heart function. Ped. Res. 40: 633-642.

Linask, Kersti K., Karen A. Knudsen, and Yong-Hao Gui.  1997.  N-Cadherin-Catenin Interaction:  Necessary component of cardiac cell compartmentalization during carly vertebrate heart development.   Dev. Biol. 185, 148-164.

Imanaka-Yoshida, Kyoko., Knudsen, Karen A., and Kersti K. Linask., 1998. N-cadherin is required for the differentiation and initial myofibrillogenesis of chick cardiomyocytes.  Cell Motility Cytoskel.  39, 52-62.

Huang, Guo-Ying and Kersti K. Linask. 1998.  Doppler echocardiographic analysis of effects of tribromoethanol anesthesia on cardiac function in the mouse embryo:  A comparison with pentobarbital. Laboratory Animal Science. 48, 206-209.

Huang, G.Y., Wessels, A., Smith B.R., Linask,  Kersti K., Ewart, J.L. and Lo, C.W. 1998.  Alterations in connexin 43 gap junction gene dosage impair conotruncal heart development. Dev. Biol.198, 32-44.

Linask, Kersti K., Ludwig, Cheryl, Han, Ming-Da, Radice, Glenn, and Knudsen, Karen A.  1998.   N-Cadherin/Catenin Mediated Morphoregulation of Somite Formation. Dev. Biol.  202, 85-102.

Kostetskii, I., Yuan, S.Y., Kostetskaia, E., Linask, Kersti K., Blanchet, S. Seleiro, E., Michaille, J.J., Brickell, P. and Zile, M.  1998.  Initial retinoid requirement for early avian development coincides with retinoid receptor coexpression in the precardiac fields and induction of normal cardiovascular development.  Dev. Dynamics.  213, 188-198.

Sullivan, R., G.Y. Huang, R.A. Meyer, A. Wessels, Linask, Kersti K., and C.W. Lo.  1998.  Heart malformations in transgenic mice exhibiting dominant negative inhibition of gap junctional communication in neural crest cells.  Dev. Biol.  204, 224-234.

Tsuda, T., Majumder, K., and Linask, Kersti K. 1998. Differential expression of flectin in the extracellular matrix and left-right asymmetry in mouse embryonic heart during looping stages. Dev. Genetics. 23, 203-214. Invited paper. (Peer reviewed)

Linask, Kersti K., 1999. A conserved developmental role of adhesion molecules in cardiac and skeletal myogenesi. Basic Applied Myology. Invited paper. 8, 293-302. (Peer reviewed)

Linask, Kersti .K., Han, M.D., Artman, M., Ludwig. 2001. Sodium-calcium exchanger (NCX-1) and calcium modulation: NCX protein expression patterns and regulation of early heart development. Dev. Dynamics. 221:249-264.

Yue, G., Lai, P.S., Yin, K., Sun, F.F., Nagele, R.G., Liu, X., Linask, Kersti K., Wang, C., Lin, K.T., and Wong, P.Y.K. 2001. Colon epithelial cell death in 2,4,6-trinitrobenzenesulfonic acid-induced colitis is associated with increased inducible nitric-oxide synthase expression and peroxynitrite production. J. Pharmacol. Exptl. Therapeutics. 297, 915-925.

Linask, Kersti .K., Yu, X., Chen, Y.P., and Han, M.D. 2002. Directionality of Heart Looping: Effects of Pitx2c misexpression on flectin asymmetry and midline structures. Dev. Biol. 246, 407-417.

Linask, Kersti K. 2003. Regulation of Heart Morphology: Current molecular and cellular perspectives on the coordinated emergence of cardiac form and function. Birth Defects, Part C. 69,14-24 Invited review paper (peer reviewed).

Du, A., Sanger, J.M., Linask, Kersti .K., and J.W. Sanger. 2003. Myofibrillogenesis in the first cardiomyocytes formed from isolated quail precardiac mesoderm. Dev. Biol. 257, 382-394.

Linask, Kaari L., Xu, X., Thomas, M.P., Li, W.E.I., Ek-Vitorin, J., Meyer, R., Wessels, A., Han, M.D., Linask, Kersti K., Taffet, S., Delmar, M., and Lo, C.W. 2003. The carboxy-terminus of connexin 43 modulates neural crest cell motility and heart development. In revision.

Linask, Kersti .K., Han, M.D., Linask, Kaari.L., Schlange, T., Brand, T. 2003. Effects of antisense misexpression of CFC on downstream flectin protein expression during heart looping. Dev. Dynamics. 228:217-230.

Manohar, Shyam., Han, Ming-Da, and Linask, Kersti K. 2003. Anterior-posterior effects of lithium on neural tube and heart development. Submitted.

Manisastry, S.M., M. Han and Kersti K. Linask. 2004. Anterior to Posterior Progression of Heart Development: Clinical Implications of Lithium Exposure. (Meeting Proceedings). 10 (Suppl 2),196-197.

Linask, Kersti K., Manisastry, S.M., and Han, M.D. 2005. Cross-talk between cell-cell and cell-matrix adhesion signaling pathways during heart organogenesis: A lithium connection and implications for cardiac birth defects. (Invited article). Microscopy and Microanalysis. 11, 200-208.

Linask, Kersti K.., Han, M.D., Cai, M., Brauer, P. Manisastry, S. 2005. Cardiac Morphogenesis: MMP-2 involvement in cellular mechanisms underlying heart tube formation and looping. Dev. Dyn. 233:739-753.

Han, M, Trotta, P., Coleman, C. and Linask, Kersti K. 2005. MCT-4, A511/Basigin and EF5 expression patterns during early chick cardiomyogenesis indicate cardiac cell differentiation occurs in a hypoxic environment. Dev. Dyn. In press.


CHAPTERS IN BOOKS (First Author):

Linask, Kersti K. 1992. Regulatory role of cell adhesion molecules in early heart development. In Formation and Differentiation of Early Embryonic Mesoderm (Lash, J.W. and Bellairs, R., eds), NATO ASI Series, Plenum Publishing Corporation, New York, NY.

Linask, Kersti K. 1993. Morphoregulation of early heart development: A role for cell adhesion molecules. Folia Baeriana (Vol. 6). [Proceedings of the International Conference on Baer and Modern Biology, Feb. 1992]. pp. 172-177.

Linask, Kersti K. and J.W. Lash. 1998. Morphoregulatory Mechanisms Underlying Early Heart Development: Precardiac Stages to the Looping, Tubular Heart. In Living Morphogenesis of the Heart. Roger Markwald and M.de La Cruz, Editors. Birkhauser Inc., Boston, pp. 1-41.

Linask, Kersti K. and T. Tsuda. 1999. In Developmental Biology Protocols (Volumes I and II). Eds. R. Tuan and C. Lo.,. Immunohistochemistry and use of plastic embedding for high resolution microscopy, Chap. 16, Humana Press, Totowa, NJ , pp. 165-173.

Linask, Kersti K. and J.C. Huhta. 1999. In Developmental Biology Protocols (Volumes I and II). Eds. R. Tuan and C. Lo., Humana Press, Totowa, NJ. Use of Doppler echocardiography to monitor embryonic mouse heart function, Chap. 24, Humana Press, Totowa, NJ , pp. 245-252 .

Linask, Kersti K. 2000. Adhesion-mediated morphoregulatory mechanisms of early cardiogenesis. In Etiology and Morphogenesis of Congenital Heart Disease: Twenty Years of Progress in Genetics and Developmental Biology. Eds. E. B. Clark, M. Nakazawa, A. Takao. Futura Publishing Co., Inc. Armonk, NY.

Linask, Kersti K., M.D. Han, Y.P. Chen, T. Brand and P. R. Brauer. 2003. Misexpression of upstream laterality genes on downstream mechanisms of heart looping: A flectin perspective. To be published in: Etiology and Morphogenesis of Congenital Cardiovascular Disease in the Post-Genomic Era. Eds. E.B. Clark and M. Nakazawa.


REPORTS:

M. Letarte, Bourdillon MC, Vera S, Pece N, Greaves A, Dignat-George F, Mutin M, Kraling B, Linask K.K., O'Brien ER, Labinaz M, Ross J, Parish C, and Bernabeu C. Cluster Report CD105 (Endoglin). 1997. Leukocyte Typing VI.

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Heartbeats of the Linask Lab

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